Dr. Rubin is Professor of Medicine with a secondary appointment as Professor of Computer Sciences at the University of Pennsylvania. The NIH, NSF, DARPA, the Global Alliance for TB Drug Discovery and the Gates Foundation have funded his basic biochemical and genetic research in infectious diseases, resulting in more than 100 peer-reviewed papers. In addition to his work on the basic biology of disease, he works on mathematical models of complex biological systems including models of the spread of infectious diseases, models of bacterial survival strategies under uncertain environmental conditions and predictive maintenance vaccine refrigeration systems using digital twins and machine learning. He served on national and international scientific review panels including the NIH, NSF, NASA Intelligent Systems Program, DARPA, and The Medical Research Council, South Africa. He was a member of the U.S. National Science Advisory Board for Biosecurity and the Dept. of Defense/National Academy of Sciences Biological Cooperative Threat Reduction Program.

Dr. Rubin’s inpatient and outpatient clinical practice at the University of Pennsylvania is focused on patients with infectious diseases. He is the founder of Energize the Chain, a non-profit organization that ensures the delivery of vaccines to people in the most remote regions of the world by utilizing energy and connectivity available at cell tower sites and solar powered sites to power the refrigeration systems that are necessary to keep vaccines at the proper temperature. He is the recipient of a 2020 Scholar in Residence award at the Rockefeller Foundation Bellagio Center, Bellagio, Italy.